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BMCBI
2011
13 years 4 months ago
R2R - software to speed the depiction of aesthetic consensus RNA secondary structures
Background: With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these mol...
Zasha Weinberg, Ronald R. Breaker
BMCBI
2011
13 years 4 months ago
Hierarchical graphs for rule-based modeling of biochemical systems
Background: In rule-based modeling, graphs are used to represent molecules: a colored vertex represents a component of a molecule, a vertex attribute represents the internal state...
Nathan W. Lemons, Bin Hu, William S. Hlavacek
BMCBI
2011
13 years 4 months ago
A quality metric for homology modeling: the H-factor
Background: The analysis of protein structures provides fundamental insight into most biochemical functions and consequently into the cause and possible treatment of diseases. As ...
Eric di Luccio, Patrice Koehl
BMCBI
2011
13 years 4 months ago
Clinical Synopsis Search in OMIM
Background: The OMIM database is a tool used daily by geneticists. Syndrome pages include a Clinical Synopsis section containing a list of known phenotypes comprising a clinical s...
Raphael Cohen, Avitan Gefen, Michael Elhadad, Ohad...
BMCBI
2011
13 years 4 months ago
Appearance frequency modulated gene set enrichment testing
Background: Gene set enrichment testing has helped bridge the gap from an individual gene to a systems biology interpretation of microarray data. Although gene sets are defined a ...
Jun Ma, Maureen A. Sartor, H. V. Jagadish