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BMCBI
2011
13 years 4 months ago
Outer membrane proteins can be simply identified using secondary structure element alignment
Background: Outer membrane proteins (OMPs) are frequently found in the outer membranes of gram-negative bacteria, mitochondria and chloroplasts and have been found to play diverse...
Ren-Xiang Yan, Zhen Chen, Ziding Zhang
BMCBI
2011
13 years 4 months ago
DecGPU: distributed error correction on massively parallel graphics processing units using CUDA and MPI
Background: Next-generation sequencing technologies have led to the high-throughput production of sequence data (reads) at low cost. However, these reads are significantly shorter...
Yongchao Liu, Bertil Schmidt, Douglas L. Maskell
BMCBI
2011
13 years 4 months ago
Implementation of Force Distribution Analysis for Molecular Dynamics simulations
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
Wolfram Stacklies, Christian Seifert, Frauke Graet...
BMCBI
2011
13 years 4 months ago
Analysis on the reconstruction accuracy of the Fitch method for inferring ancestral states
Background: As one of the most widely used parsimony methods for ancestral reconstruction, the Fitch method minimizes the total number of hypothetical substitutions along all bran...
Jialiang Yang, Jun Li, Liuhuan Dong, Stefan Gr&uum...
BMCBI
2011
13 years 1 months ago
Structator: fast index-based search for RNA sequence-structure patterns
Background: The secondary structure of RNA molecules is intimately related to their function and often more conserved than the sequence. Hence, the important task of searching dat...
Fernando Meyer, Stefan Kurtz, Rolf Backofen, Sebas...