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BMCBI
2011
13 years 4 months ago
2011
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
BMCBI
2011
13 years 4 months ago
2011
Background: Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genotyping every s...
BMCBI
2011
13 years 4 months ago
2011
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
BMCBI
2011
13 years 1 months ago
2011
Background: The cost efficient two-stage design is often used in genome-wide association studies (GWASs) in searching for genetic loci underlying the susceptibility for complex di...
BMCBI
2011
13 years 1 months ago
2011
Background: Chromatin immunoprecipitation (ChIP), coupled with massively parallel short-read sequencing (seq) is used to probe chromatin dynamics. Although there are many algorith...