Background: Liquid chromatography-mass spectrometry (LC-MS) utilizing the high-resolution power of an orbitrap is an important analytical technique for both metabolomics and prote...
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
Alexander Y. Panchin, Sergey I. Mitrofanov, Andrei...
Background: Gene-gene epistatic interactions likely play an important role in the genetic basis of many common diseases. Recently, machine-learning and data mining methods have be...
Xia Jiang, Richard E. Neapolitan, M. Michael Barma...
Background: Atomic Solvation Parameters (ASP) model has been proven to be a very successful method of calculating the binding free energy of protein complexes. This suggests that ...
Lin Li, Dachuan Guo, Yangyu Huang, Shiyong Liu, Yi...
Background: Genomic position (GP) files currently used in next-generation sequencing (NGS) studies are always difficult to manipulate due to their huge size and the lack of approp...