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APIN
2008
100views more  APIN 2008»
13 years 8 months ago
A case-based approach for characterization and analysis of subgroup patterns
In general, cases capture knowledge and concrete experiences of specific situations. By exploiting case-based knowledge for characterizing a subgroup pattern, additional informati...
Martin Atzmüller, Frank Puppe
AUTOMATICA
2008
74views more  AUTOMATICA 2008»
13 years 8 months ago
Policy iteration based feedback control
It is well known that stochastic control systems can be viewed as Markov decision processes (MDPs) with continuous state spaces. In this paper, we propose to apply the policy iter...
Kan-Jian Zhang, Yan-Kai Xu, Xi Chen, Xi-Ren Cao
BIOINFORMATICS
2008
119views more  BIOINFORMATICS 2008»
13 years 8 months ago
Optimal design of thermally stable proteins
Motivation: For many biotechnological purposes, it is desirable to redesign proteins to be more structurally and functionally stable at higher temperatures. For example, chemical ...
Ryan M. Bannen, Vanitha Suresh, George N. Phillips...
BMCBI
2008
136views more  BMCBI 2008»
13 years 8 months ago
A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model
Background: Bioactivity profiling using high-throughput in vitro assays can reduce the cost and time required for toxicological screening of environmental chemicals and can also r...
Richard Judson, Fathi Elloumi, R. Woodrow Setzer, ...
BMCBI
2008
76views more  BMCBI 2008»
13 years 8 months ago
Empirical Bayes analysis of single nucleotide polymorphisms
Background: An important goal of whole-genome studies concerned with single nucleotide polymorphisms (SNPs) is the identification of SNPs associated with a covariate of interest s...
Holger Schwender, Katja Ickstadt