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BMCBI
2006
202views more  BMCBI 2006»
15 years 3 months ago
Spectral embedding finds meaningful (relevant) structure in image and microarray data
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
Brandon W. Higgs, Jennifer W. Weller, Jeffrey L. S...
BMCBI
2006
99views more  BMCBI 2006»
15 years 3 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2006
119views more  BMCBI 2006»
15 years 3 months ago
A methodology for the structural and functional analysis of signaling and regulatory networks
Background: Structural analysis of cellular interaction networks contributes to a deeper understanding of network-wide interdependencies, causal relationships, and basic functiona...
Steffen Klamt, Julio Saez-Rodriguez, Jonathan A. L...
BMCBI
2006
143views more  BMCBI 2006»
15 years 3 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...
BMCBI
2006
92views more  BMCBI 2006»
15 years 3 months ago
Recrafting the neighbor-joining method
Background: The neighbor-joining method by Saitou and Nei is a widely used method for constructing phylogenetic trees. The formulation of the method gives rise to a canonical (n3)...
Thomas Mailund, Gerth Stølting Brodal, Rolf...