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157
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BMCBI
2010
105views more  BMCBI 2010»
15 years 4 months ago
GWAMA: software for genome-wide association meta-analysis
Background: Despite the recent success of genome-wide association studies in identifying novel loci contributing effects to complex human traits, such as type 2 diabetes and obesi...
Reedik Mägi, Andrew P. Morris
BMCBI
2010
167views more  BMCBI 2010»
15 years 4 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
162
Voted
BMCBI
2010
154views more  BMCBI 2010»
15 years 4 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2010
190views more  BMCBI 2010»
15 years 4 months ago
A parallel and incremental algorithm for efficient unique signature discovery on DNA databases
Background: DNA signatures are distinct short nucleotide sequences that provide valuable information that is used for various purposes, such as the design of Polymerase Chain Reac...
Hsiao Ping Lee, Tzu-Fang Sheu, Chuan Yi Tang
136
Voted
BMCBI
2010
113views more  BMCBI 2010»
15 years 4 months ago
Gene prioritization and clustering by multi-view text mining
Background: Text mining has become a useful tool for biologists trying to understand the genetics of diseases. In particular, it can help identify the most interesting candidate g...
Shi Yu, Léon-Charles Tranchevent, Bart De M...