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135
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BMCBI
2010
83views more  BMCBI 2010»
15 years 4 months ago
An effective approach for generating a three-Cys2His2 zinc-finger-DNA complex model by docking
Background: Determination of protein-DNA complex structures with both NMR and X-ray crystallography remains challenging in many cases. High Ambiguity-Driven DOCKing (HADDOCK) is a...
Chun-Chi Chou, M. Rajasekaran, Chinpan Chen
BMCBI
2010
167views more  BMCBI 2010»
15 years 4 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
BMCBI
2010
113views more  BMCBI 2010»
15 years 4 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...
ECCC
2007
147views more  ECCC 2007»
15 years 3 months ago
Inapproximability of edge-disjoint paths and low congestion routing on undirected graphs
In the undirected Edge-Disjoint Paths problem with Congestion (EDPwC), we are given an undirected graph with V nodes, a set of terminal pairs and an integer c. The objective is to...
Matthew Andrews, Julia Chuzhoy, Venkatesan Guruswa...
135
Voted
ECCC
1998
118views more  ECCC 1998»
15 years 3 months ago
Chinese Remaindering with Errors
The Chinese Remainder Theorem states that a positive integer m is uniquely speci ed by its remainder modulo k relatively prime integers p1;:::;pk, provided m < Qk i=1 pi. Thus ...
Oded Goldreich, Dana Ron, Madhu Sudan