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CIBCB
2008
IEEE
14 years 1 months ago
Temporal and structural analysis of biological networks in combination with microarray data
— We introduce a graph-based relational learning approach using graph-rewriting rules for temporal and structural analysis of biological networks changing over time. The analysis...
Chang Hun You, Lawrence B. Holder, Diane J. Cook
CIBCB
2008
IEEE
14 years 1 months ago
Discovering novel cancer therapies: A computational modeling and search approach
— Solid tumors must recruit new blood vessels for growth and maintenance. Discovering drugs that block this tumor-induced development of new blood vessels (angiogenesis) is an im...
Arthur W. Mahoney, Brian G. Smith, Nicholas S. Fla...
CIBCB
2008
IEEE
14 years 1 months ago
Very large scale ReliefF for genome-wide association analysis
— The genetic causes of many monogenic diseases have already been discovered. However, most common diseases are actually the result of complex nonlinear interactions between mult...
Margaret J. Eppstein, Paul Haake
CIBCB
2009
IEEE
13 years 8 months ago
Improved prediction of trans-membrane spans in proteins using an artificial neural network
Tools for the identification of trans-membrane spans from the protein sequence are widely used in the experimental community. Computational structural biology seeks to increase the...
Julia Koehler, Ralf Mueller, Jens Meiler