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165
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BMCBI
2010
15 years 4 months ago
2010
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
178
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BMCBI
2010
15 years 4 months ago
2010
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
114
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BMCBI
2010
15 years 4 months ago
2010
Background: Protein-protein docking for proteins with large conformational changes was analyzed by using interaction fingerprints, one of the scales for measuring similarities amo...
133
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BMCBI
2010
15 years 4 months ago
2010
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
138
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BMCBI
2010
15 years 4 months ago
2010
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...