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BMCBI
2010
128views more  BMCBI 2010»
15 years 4 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
TIP
2010
97views more  TIP 2010»
14 years 11 months ago
Image Clustering Using Local Discriminant Models and Global Integration
In this paper, we propose a new image clustering algorithm, referred to as Clustering using Local Discriminant Models and Global Integration (LDMGI). To deal with the data points s...
Yi Yang, Dong Xu, Feiping Nie, Shuicheng Yan, Yuet...
BMCBI
2010
139views more  BMCBI 2010»
15 years 4 months ago
A highly efficient multi-core algorithm for clustering extremely large datasets
Background: In recent years, the demand for computational power in computational biology has increased due to rapidly growing data sets from microarray and other high-throughput t...
Johann M. Kraus, Hans A. Kestler
BMCBI
2010
145views more  BMCBI 2010»
15 years 4 months ago
Clustering metagenomic sequences with interpolated Markov models
Background: Sequencing of environmental DNA (often called metagenomics) has shown tremendous potential to uncover the vast number of unknown microbes that cannot be cultured and s...
David R. Kelley, Steven L. Salzberg
BMCBI
2010
151views more  BMCBI 2010»
15 years 4 months ago
Data reduction for spectral clustering to analyze high throughput flow cytometry data
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...