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BMCBI
2006
153views more  BMCBI 2006»
13 years 11 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
BMCBI
2006
150views more  BMCBI 2006»
13 years 11 months ago
Predicting protein subcellular locations using hierarchical ensemble of Bayesian classifiers based on Markov chains
Background: The subcellular location of a protein is closely related to its function. It would be worthwhile to develop a method to predict the subcellular location for a given pr...
Alla Bulashevska, Roland Eils
BMCBI
2006
115views more  BMCBI 2006»
13 years 11 months ago
AgdbNet - antigen sequence database software for bacterial typing
Background: Bacterial typing schemes based on the sequences of genes encoding surface antigens require databases that provide a uniform, curated, and widely accepted nomenclature ...
Keith A. Jolley, Martin C. J. Maiden
BMCBI
2006
130views more  BMCBI 2006»
13 years 11 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
BMCBI
2006
97views more  BMCBI 2006»
13 years 11 months ago
REEF: searching REgionally Enriched Features in genomes
Background: In Eukaryotic genomes, different features including genes are not uniformly distributed. The integration of annotation information and genomic position of functional D...
Alessandro Coppe, Gian Antonio Danieli, Stefania B...