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BMCBI
2006
127views more  BMCBI 2006»
13 years 11 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2006
111views more  BMCBI 2006»
13 years 11 months ago
Tools for integrated sequence-structure analysis with UCSF Chimera
Background: Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many pr...
Elaine C. Meng, Eric F. Pettersen, Gregory S. Couc...
BMCBI
2006
128views more  BMCBI 2006»
13 years 11 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
BMCBI
2006
114views more  BMCBI 2006»
13 years 11 months ago
Impact of RNA structure on the prediction of donor and acceptor splice sites
Background: gene identification in genomic DNA sequences by computational methods has become an important task in bioinformatics and computational gene prediction tools are now es...
Sayed-Amir Marashi, Changiz Eslahchi, Hamid Pezesh...
BMCBI
2006
146views more  BMCBI 2006»
13 years 11 months ago
A database application for pre-processing, storage and comparison of mass spectra derived from patients and controls
Background: Statistical comparison of peptide profiles in biomarker discovery requires fast, userfriendly software for high throughput data analysis. Important features are flexib...
Mark K. Titulaer, Ivar Siccama, Lennard J. Dekker,...