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BMCBI
2004
110views more  BMCBI 2004»
13 years 8 months ago
Tools for loading MEDLINE into a local relational database
Background: Researchers who use MEDLINE for text mining, information extraction, or natural language processing may benefit from having a copy of MEDLINE that they can manage loca...
Diane E. Oliver, Gaurav Bhalotia, Ariel S. Schwart...
BMCBI
2004
123views more  BMCBI 2004»
13 years 8 months ago
A two-way interface between limited Systems Biology Markup Language and R
Background: Systems Biology Markup Language (SBML) is gaining broad usage as a standard for representing dynamical systems as data structures. The open source statistical programm...
Tomas Radivoyevitch
BMCBI
2004
151views more  BMCBI 2004»
13 years 8 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
BMCBI
2004
97views more  BMCBI 2004»
13 years 8 months ago
Global features of sequences of bacterial chromosomes, plasmids and phages revealed by analysis of oligonucleotide usage pattern
Background: Oligonucleotide frequencies were shown to be conserved signatures for bacterial genomes, however, the underlying constraints have yet not been resolved in detail. In t...
Oleg N. Reva, Burkhard Tümmler
BMCBI
2004
141views more  BMCBI 2004»
13 years 8 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
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