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BMCBI
2005
85views more  BMCBI 2005»
13 years 9 months ago
Processing methods for differential analysis of LC/MS profile data
Background: Liquid chromatography coupled to mass spectrometry (LC/MS) has been widely used in proteomics and metabolomics research. In this context, the technology has been incre...
Mikko Katajamaa, Matej Oresic
BMCBI
2005
124views more  BMCBI 2005»
13 years 9 months ago
ErmineJ: Tool for functional analysis of gene expression data sets
Background: It is common for the results of a microarray study to be analyzed in the context of biologically-motivated groups of genes such as pathways or Gene Ontology categories...
Homin K. Lee, William Braynen, Kiran Keshav, Paul ...
BMCBI
2005
122views more  BMCBI 2005»
13 years 9 months ago
Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein
Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
Jiajian Liu, Gary D. Stormo
BMCBI
2005
158views more  BMCBI 2005»
13 years 9 months ago
Automated generation of heuristics for biological sequence comparison
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
Guy St. C. Slater, Ewan Birney
BMCBI
2005
156views more  BMCBI 2005»
13 years 9 months ago
A new dynamical layout algorithm for complex biochemical reaction networks
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Katja Wegner, Ursula Kummer