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BMCBI
2005
97views more  BMCBI 2005»
13 years 7 months ago
Sequence variation in ligand binding sites in proteins
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
Thomas J. Magliery, Lynne Regan
BMCBI
2005
123views more  BMCBI 2005»
13 years 7 months ago
PSI-BLAST-ISS: an intermediate sequence search tool for estimation of the position-specific alignment reliability
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2005
61views more  BMCBI 2005»
13 years 7 months ago
Proteins with two SUMO-like domains in chromatin-associated complexes: The RENi (Rad60-Esc2-NIP45) family
Background: Post-translational modification by Small Ubiquitin-like Modifiers (SUMO) has been implicated in protein targeting, in the maintenance of genomic integrity and in trans...
Maria Novatchkova, Andreas Bachmair, Birgit Eisenh...
BMCBI
2005
251views more  BMCBI 2005»
13 years 7 months ago
Contextual weighting for Support Vector Machines in literature mining: an application to gene versus protein name disambiguation
Background: The ability to distinguish between genes and proteins is essential for understanding biological text. Support Vector Machines (SVMs) have been proven to be very effici...
Tapio Pahikkala, Filip Ginter, Jorma Boberg, Jouni...
BMCBI
2005
104views more  BMCBI 2005»
13 years 7 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...