Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
Background: An algorithm is presented to compute a multiple structure alignment for a set of proteins and to generate a consensus (pseudo) protein which captures common substructu...
Background: Determining a suitable sample size is an important step in the planning of microarray experiments. Increasing the number of arrays gives more statistical power, but ad...
Ilari Scheinin, Jose A. Ferreira, Sakari Knuutila,...