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156
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BMCBI
2010
15 years 6 months ago
2010
Background: Our current understanding of transcription factor binding sites (TFBSs) in sequenced prokaryotic genomes is very limited due to the lack of an accurate and efficient c...
140
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BMCBI
2010
15 years 6 months ago
2010
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
149
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BMCBI
2010
15 years 6 months ago
2010
Background: Recent advances in antibody microarray technology have made it possible to measure the expression of hundreds of proteins simultaneously in a competitive dual-colour a...
191
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BMCBI
2010
15 years 6 months ago
2010
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
154
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BMCBI
2010
15 years 6 months ago
2010
Background: Genome sequencing projects have expanded the gap between the amount of known protein sequences and structures. The limitations of current high resolution structure det...