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CSB
2005
IEEE
110views Bioinformatics» more  CSB 2005»
15 years 11 months ago
A Topological Measurement for Weighted Protein Interaction Network
High-throughput methods for detecting protein-protein interactions (PPI) have given researchers an initial global picture of protein interactions on a genomic scale. The usefulnes...
Pengjun Pei, Aidong Zhang
CSB
2005
IEEE
115views Bioinformatics» more  CSB 2005»
15 years 11 months ago
A New Clustering Strategy with Stochastic Merging and Removing Based on Kernel Functions
With hierarchical clustering methods, divisions or fusions, once made, are irrevocable. As a result, when two elements in a bottom-up algorithm are assigned to one cluster, they c...
Huimin Geng, Hesham H. Ali
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CSB
2005
IEEE
143views Bioinformatics» more  CSB 2005»
15 years 11 months ago
Multivariate gene selection: Does it help
When building predictors of disease state based on gene expression data, gene selection is performed in order to achieve a good performance and to identify a relevant subset of ge...
Carmen Lai, Marcel J. T. Reinders
CSB
2005
IEEE
165views Bioinformatics» more  CSB 2005»
15 years 7 months ago
Sequential Diagonal Linear Discriminant Analysis (SeqDLDA) for Microarray Classification and Gene Identification
In microarray classification we are faced with a very large number of features and very few training samples. This is a challenge for classical Linear Discriminant Analysis (LDA),...
Roger Pique-Regi, Antonio Ortega, Shahab Asgharzad...
CSB
2005
IEEE
133views Bioinformatics» more  CSB 2005»
15 years 11 months ago
Biological Pathway Prediction from Multiple Data Sources Using Iterative Bayesian Updating
There is a diversity of functional genomics data, such as gene expression data from microarray experiments, phenotypic data from gene deletion experiments, protein-protein interac...
Corey Powell, Joshua M. Stuart