Using current technology, large consecutive stretches of DNA (such as whole chromosomes) are usually assembled from short fragments obtained by shotgun sequencing, or from fragment...
Daniel H. Huson, Aaron L. Halpern, Zhongwu Lai, Eu...
DNA arrays can be used to measure the expression levels of thousands of genes simultaneously. Currently most research focuses on the interpretation of the meaning of the data. How...
Chun Tang, Li Zhang, Aidong Zhang, Murali Ramanath...
During the last decade, the area of bioinformatics has produced an overwhelming amount of data, with the recently published draft of the human genome being the most prominent exam...
motif discovery problem abstracts the task of discovering short, conserved sites in genomic DNA. Pevzner and Sze recently described a precise combinatorial formulation of motif di...
Abstract. Single nucleotide polymorphisms (SNPs) are the most frequent form of human genetic variation. They are of fundamental importance for a variety of applications including m...
Giuseppe Lancia, Vineet Bafna, Sorin Istrail, Ross...