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APBC
2003
13 years 8 months ago
Inferring an Original Sequence from Erroneous Copies : A Bayesian Approach
This paper considers the problem of inferring an original sequence from a number of erroneous copies. The problem arises in DNA sequencing, particularly in the context of emerging...
Jonathan M. Keith, Peter Adams, Darryn E. Bryant, ...
CSB
2003
IEEE
108views Bioinformatics» more  CSB 2003»
14 years 23 days ago
A Pattern Matching Algorithm for Codon Optimization and CpG Motif-Engineering in DNA Expression Vectors
Codon optimization enhances the efficiency of DNA expression vectors used in DNA vaccination and gene therapy by increasing protein expression. Additionally, certain nucleotide mo...
Ravi Vijaya Satya, Amar Mukherjee, Udaykumar Ranga
AI
2003
Springer
14 years 22 days ago
Hybrid Randomised Neighbourhoods Improve Stochastic Local Search for DNA Code Design
Sets of DNA strands that satisfy combinatorial constraints play an important role in various approaches to biomolecular computation, nanostructure design, and molecular tagging. Th...
Dan C. Tulpan, Holger H. Hoos
GECCO
2003
Springer
129views Optimization» more  GECCO 2003»
14 years 21 days ago
Evolutionary Two-Dimensional DNA Sequence Alignment
This article presents a model for DNA sequence alignment. In our model, a finite state automaton writes two-dimensional maps of nucleotide sequences. An evolutionary method for se...
Edgar E. Vallejo, Fernando Ramos
RECOMB
2003
Springer
14 years 7 months ago
Towards optimally multiplexed applications of universal DNA tag systems
We study a design and optimization problem that occurs, for example, when single nucleotide polymorphisms (SNPs) are to be genotyped using a universal DNA tag array. The problem o...
Amir Ben-Dor, Tzvika Hartman, Benno Schwikowski, R...