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BMCBI
2004
128views more  BMCBI 2004»
13 years 8 months ago
Comparing transformation methods for DNA microarray data
Background: When DNA microarray data are used for gene clustering, genotype/phenotype correlation studies, or tissue classification the signal intensities are usually transformed ...
Helene H. Thygesen, Aeilko H. Zwinderman
BIOCOMP
2006
13 years 9 months ago
Melting Free Energies of DNA Duplexes with oxidized Base Residues and Abasic sites: A Molecular Dynamics Characterization
: Ionizing radiation alters DNA strands and mainly creates multiply damaged sites (MDS), e.g. two or more damaged sites within one or two turns of the DNA (10 to 20 base pairs). Th...
Latifa Douali, Matt Ernst, John Miller, Michel Dup...
BMCBI
2006
108views more  BMCBI 2006»
13 years 8 months ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
BIBE
2007
IEEE
133views Bioinformatics» more  BIBE 2007»
14 years 2 months ago
Denoising of Array-Based DNA Copy Number Data Using The Dual-tree Complex Wavelet Transform
—Array-based comparative genomic hybridization (array CGH) is a highly efficient technique, allowing the simultaneous measurement of genomic DNA copy number at hundreds or thous...
Nha Nguyen, Heng Huang, Soontorn Oraintara, Yuhang...
BMCBI
2004
120views more  BMCBI 2004»
13 years 8 months ago
Optimal cDNA microarray design using expressed sequence tags for organisms with limited genomic information
Background: Expression microarrays are increasingly used to characterize environmental responses and hostparasite interactions for many different organisms. Probe selection for cD...
Yian A. Chen, David J. Mckillen, Shuyuan Wu, Matth...