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JCC
2008
138views more  JCC 2008»
13 years 9 months ago
Circular dichroism enhancement in large DNA aggregates simulated by a generalized oscillator model
Abstract: An increased circular dichroism (CD) signal of large molecular aggregates formed upon DNA condensation was observed a long time ago, and is often referred to as w-CD. The...
Valery Andrushchenko, Petr Bour
BMCBI
2008
111views more  BMCBI 2008»
13 years 9 months ago
Aspects of coverage in medical DNA sequencing
Background: DNA sequencing is now emerging as an important component in biomedical studies of diseases like cancer. Short-read, highly parallel sequencing instruments are expected...
Michael C. Wendl, Richard K. Wilson
DISOPT
2007
93views more  DISOPT 2007»
13 years 9 months ago
A polynomial time equivalence between DNA sequencing and the exact perfect matching problem
We investigate the computational complexity of a combinatorial problem that arises in DNA sequencing by hybridization: The input consists of an integer together with a set S of wo...
Jacek Blazewicz, Piotr Formanowicz, Marta Kasprzak...
TSMC
2008
93views more  TSMC 2008»
13 years 9 months ago
Selection of DNA Markers
Given a genome, i.e., a long string over a fixed finite alphabet, the problem is to find short (dis)similar substrings. This computationally intensive task has many biological appl...
Hendrik Jan Hoogeboom, Walter A. Kosters, Jeroen F...
BIBE
2008
IEEE
150views Bioinformatics» more  BIBE 2008»
13 years 9 months ago
Automatic DNA microarray gridding based on Support Vector Machines
This paper presents a novel method for DNA microarray gridding based on Support Vector Machine (SVM) classifiers. It employs a set of soft-margin SVMs to estimate the lines of the ...
Dimitris G. Bariamis, Dimitris Maroulis, Dimitrios...