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ALGORITHMICA
2011
13 years 5 months ago
2011
Let G = (V, E, w) be a directed graph, where w : V → R is an arbitrary weight function defined on its vertices. The bottleneck weight, or the capacity, of a path is the smalles...
BMCBI
2010
13 years 5 months ago
2010
Background: Shared-usage high throughput screening (HTS) facilities are becoming more common in academe as large-scale small molecule and genome-scale RNAi screening strategies ar...
BMCBI
2010
13 years 5 months ago
2010
Background: The functional and structural characterisation of enzymes that belong to microbial metabolic pathways is very important for structure-based drug design. The main inter...
BMCBI
2010
13 years 5 months ago
2010
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...
BMCBI
2010
13 years 5 months ago
2010
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...