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BMCBI
2010
155views more  BMCBI 2010»
15 years 4 months ago
FunctSNP: an R package to link SNPs to functional knowledge and dbAutoMaker: a suite of Perl scripts to build SNP databases
Background: Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a ...
Stephen J. Goodswen, Cedric Gondro, Nathan S. Wats...
BMCBI
2010
132views more  BMCBI 2010»
15 years 4 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
148
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BMCBI
2010
124views more  BMCBI 2010»
15 years 4 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2010
132views more  BMCBI 2010»
15 years 4 months ago
Data structures and compression algorithms for high-throughput sequencing technologies
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
Kenny Daily, Paul Rigor, Scott Christley, Xiaohui ...
139
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ECOI
2007
101views more  ECOI 2007»
15 years 4 months ago
Reasoning about taxonomies in first-order logic
Experts often disagree about the organization of biological taxa. The shifting definitions of taxonomic names complicate otherwise simple queries concerning these taxa. For examp...
David Thau, Bertram Ludäscher