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BMCBI
2005
113views more  BMCBI 2005»
13 years 8 months ago
Normal uniform mixture differential gene expression detection for cDNA microarrays
Background: One of the primary tasks in analysing gene expression data is finding genes that are differentially expressed in different samples. Multiple testing issues due to the ...
Nema Dean, Adrian E. Raftery
BMCBI
2005
90views more  BMCBI 2005»
13 years 8 months ago
TMB-Hunt: An amino acid composition based method to screen proteomes for beta-barrel transmembrane proteins
Background: Beta-barrel transmembrane (bbtm) proteins are a functionally important and diverse group of proteins expressed in the outer membranes of bacteria (both gram negative a...
Andrew G. Garrow, Alison Agnew, David R. Westhead
BMCBI
2005
134views more  BMCBI 2005»
13 years 8 months ago
Ancestral sequence alignment under optimal conditions
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Alexander K. Hudek, Daniel G. Brown 0001
BMCBI
2005
97views more  BMCBI 2005»
13 years 8 months ago
Clustering the annotation space of proteins
Background: Current protein clustering methods rely on either sequence or functional similarities between proteins, thereby limiting inferences to one of these areas. Results: Her...
Victor Kunin, Christos A. Ouzounis
BMCBI
2005
117views more  BMCBI 2005»
13 years 8 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai