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ALMOB
2006
89views more  ALMOB 2006»
13 years 7 months ago
On the maximal cliques in c-max-tolerance graphs and their application in clustering molecular sequences
Given a set S of n locally aligned sequences, it is a needed prerequisite to partition it into groups of very similar sequences to facilitate subsequent computations, such as the ...
Katharina Anna Lehmann, Michael Kaufmann, Stephan ...
BMCBI
2006
239views more  BMCBI 2006»
13 years 7 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2006
88views more  BMCBI 2006»
13 years 7 months ago
A two-sample Bayesian t-test for microarray data
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...
Richard J. Fox, Matthew W. Dimmic
BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins