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BMCBI
2010
121views more  BMCBI 2010»
13 years 10 months ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen
BMCBI
2010
151views more  BMCBI 2010»
13 years 10 months ago
Misty Mountain clustering: application to fast unsupervised flow cytometry gating
Background: There are many important clustering questions in computational biology for which no satisfactory method exists. Automated clustering algorithms, when applied to large,...
István P. Sugár, Stuart C. Sealfon
BMCBI
2010
135views more  BMCBI 2010»
13 years 10 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
BMCBI
2010
122views more  BMCBI 2010»
13 years 10 months ago
Fast and accurate protein substructure searching with simulated annealing and GPUs
Background: Searching a database of protein structures for matches to a query structure, or occurrences of a structural motif, is an important task in structural biology and bioin...
Alex Stivala, Peter J. Stuckey, Anthony Wirth
DAM
2010
112views more  DAM 2010»
13 years 10 months ago
New results on optimizing rooted triplets consistency
Abstract. A set of phylogenetic trees with overlapping leaf sets is consistent if it can be merged without conflicts into a supertree. In this paper, we study the polynomial-time a...
Jaroslaw Byrka, Sylvain Guillemot, Jesper Jansson