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BMCBI
2008
158views more  BMCBI 2008»
13 years 7 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
BMCBI
2006
99views more  BMCBI 2006»
13 years 7 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2006
121views more  BMCBI 2006»
13 years 7 months ago
Evaluation of sequence alignments and oligonucleotide probes with respect to three-dimensional structure of ribosomal RNA using
Background: Availability of high-resolution RNA crystal structures for the 30S and 50S ribosomal subunits and the subsequent validation of comparative secondary structure models h...
Yadhu Kumar, Ralf Westram, Peter Kipfer, Harald Me...
BMCBI
2006
126views more  BMCBI 2006»
13 years 7 months ago
OpWise: Operons aid the identification of differentially expressed genes in bacterial microarray experiments
Background: Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no...
Morgan N. Price, Adam P. Arkin, Eric J. Alm
BMCBI
2006
86views more  BMCBI 2006»
13 years 7 months ago
Microbial identification by mass cataloging
Background: The public availability of over 180,000 bacterial 16S ribosomal RNA (rRNA) sequences has facilitated microbial identification and classification using hybridization an...
Zhengdong Zhang, George W. Jackson, George E. Fox,...