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BMCBI
2006
94views more  BMCBI 2006»
13 years 8 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...
BMCBI
2006
78views more  BMCBI 2006»
13 years 8 months ago
Modelling study of dimerization in mammalian defensins
Background: Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes. Their cationicity, amphipa...
Anita Suresh, Chandra Verma
BMCBI
2006
111views more  BMCBI 2006»
13 years 8 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
BMCBI
2006
147views more  BMCBI 2006»
13 years 8 months ago
Grouping Gene Ontology terms to improve the assessment of gene set enrichment in microarray data
Background: Gene Ontology (GO) terms are often used to assess the results of microarray experiments. The most common way to do this is to perform Fisher's exact tests to find...
Alex Lewin, Ian C. Grieve
BMCBI
2006
105views more  BMCBI 2006»
13 years 8 months ago
CRNPRED: highly accurate prediction of one-dimensional protein structures by large-scale critical random networks
Background: One-dimensional protein structures such as secondary structures or contact numbers are useful for three-dimensional structure prediction and helpful for intuitive unde...
Akira R. Kinjo, Ken Nishikawa
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