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156
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BMCBI
2008
15 years 4 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
166
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BMCBI
2008
15 years 4 months ago
2008
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
114
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BMCBI
2008
15 years 4 months ago
2008
Background: Repbase is a reference database of eukaryotic repetitive DNA, which includes prototypic sequences of repeats and basic information described in annotations. Repbase al...
140
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BMCBI
2008
15 years 4 months ago
2008
Background: This paper addresses key biological problems and statistical issues in the analysis of large gene expression data sets that describe systemic temporal response cascade...
126
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BMCBI
2008
15 years 4 months ago
2008
Background: Interaction data for a given protein may be spread across multiple databases. We set out to create a unifying index that would facilitate searching for these data and ...