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BMCBI
2006
167views more  BMCBI 2006»
13 years 7 months ago
GOurmet: A tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributi
Background: The ever-expanding population of gene expression profiles (EPs) from specified cells and tissues under a variety of experimental conditions is an important but difficu...
Jason M. Doherty, Lynn K. Carmichael, Jason C. Mil...
BMCBI
2006
121views more  BMCBI 2006»
13 years 7 months ago
Evaluation of sequence alignments and oligonucleotide probes with respect to three-dimensional structure of ribosomal RNA using
Background: Availability of high-resolution RNA crystal structures for the 30S and 50S ribosomal subunits and the subsequent validation of comparative secondary structure models h...
Yadhu Kumar, Ralf Westram, Peter Kipfer, Harald Me...
BMCBI
2006
89views more  BMCBI 2006»
13 years 7 months ago
A joint model for nonparametric functional mapping of longitudinal trajectory and time-to-event
Background: The characterization of the relationship between a longitudinal response process and a time-to-event has been a pressing challenge in biostatistical research. This has...
Min Lin, Rongling Wu
BMCBI
2006
132views more  BMCBI 2006»
13 years 7 months ago
Length-dependent prediction of protein intrinsic disorder
Background: Due to the functional importance of intrinsically disordered proteins or protein regions, prediction of intrinsic protein disorder from amino acid sequence has become ...
Kang Peng, Predrag Radivojac, Slobodan Vucetic, A....
BMCBI
2006
147views more  BMCBI 2006»
13 years 7 months ago
A case study in pathway knowledgebase verification
Background: Biological databases and pathway knowledgebases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we...
Stephen A. Racunas, Nigam Shah, Nina V. Fedoroff