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BMCBI
2010
13 years 10 months ago
2010
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
BMCBI
2010
13 years 10 months ago
2010
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
BMCBI
2010
13 years 10 months ago
2010
Background: Folding of a protein into its three dimensional structure is influenced by both local and global interactions within a protein. Higher order residue interactions, like...
BMCBI
2010
13 years 10 months ago
2010
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
BMCBI
2010
13 years 10 months ago
2010
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...