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BMCBI
2008
132views more  BMCBI 2008»
13 years 11 months ago
SCOWLP classification: Structural comparison and analysis of protein binding regions
Background: Detailed information about protein interactions is critical for our understanding of the principles governing protein recognition mechanisms. The structures of many pr...
Joan Teyra, Maciej Paszkowski-Rogacz, Gerd Anders,...
BMCBI
2008
89views more  BMCBI 2008»
13 years 11 months ago
Increasing the efficiency of bacterial transcription simulations: When to exclude the genome without loss of accuracy
Background: Simulating the major molecular events inside an Escherichia coli cell can lead to a very large number of reactions that compose its overall behaviour. Not only should ...
Marco A. J. Iafolla, Guang Qiang Dong, David R. Mc...
BMCBI
2008
160views more  BMCBI 2008»
13 years 11 months ago
VariVis: a visualisation toolkit for variation databases
Background: With the completion of the Human Genome Project and recent advancements in mutation detection technologies, the volume of data available on genetic variations has rise...
Timothy D. Smith, Richard G. H. Cotton
BMCBI
2008
187views more  BMCBI 2008»
13 years 11 months ago
PSAT: A web tool to compare genomic neighborhoods of multiple prokaryotic genomes
Background: The conservation of gene order among prokaryotic genomes can provide valuable insight into gene function, protein interactions, or events by which genomes have evolved...
Christine Fong, Laurence Rohmer, Matthew Radey, Mi...
BMCBI
2008
122views more  BMCBI 2008»
13 years 11 months ago
High-throughput bioinformatics with the Cyrille2 pipeline system
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...