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JCB
1998
84views more  JCB 1998»
13 years 7 months ago
Methods and Statistics for Combining Motif Match Scores
Position-speci c scoring matrices are useful for representing and searching for protein sequence motifs. A sequence family can often be described by a group of one or more motifs,...
Timothy L. Bailey, Michael Gribskov
JCB
2008
111views more  JCB 2008»
13 years 7 months ago
Sorting Genomes with Centromeres by Translocations
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromer...
Michal Ozery-Flato, Ron Shamir
JCB
2006
126views more  JCB 2006»
13 years 7 months ago
Combinatorics of Saturated Secondary Structures of RNA
Following Zuker (1986), a saturated secondary structure for a given RNA sequence is a secondary structure such that no base pair can be added without violating the definition of s...
P. Clote
JCB
2006
79views more  JCB 2006»
13 years 7 months ago
A Stability Boundary Based Method for Finding Saddle Points on Potential Energy Surfaces
The task of finding saddle points on potential energy surfaces plays a crucial role in understanding the dynamics of a micromolecule as well as in studying the folding pathways of...
Chandan K. Reddy, Hsiao-Dong Chiang
JCB
2000
101views more  JCB 2000»
13 years 7 months ago
Evaluation Measures of Multiple Sequence Alignments
Multiple sequence alignments (MSAs) are frequently used in the study of families of protein sequences or DNA/RNA sequences. They are a fundamental tool for the understanding of th...
Gaston H. Gonnet, Chantal Korostensky, Steven A. B...