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BMCBI
2006
124views more  BMCBI 2006»
13 years 9 months ago
Network-based de-noising improves prediction from microarray data
Background: Prediction of human cell response to anti-cancer drugs (compounds) from microarray data is a challenging problem, due to the noise properties of microarrays as well as...
Tsuyoshi Kato, Yukio Murata, Koh Miura, Kiyoshi As...
BMCBI
2006
94views more  BMCBI 2006»
13 years 9 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...
BMCBI
2006
117views more  BMCBI 2006»
13 years 9 months ago
The Cluster Variation Method for Efficient Linkage Analysis on Extended Pedigrees
Background: Computing exact multipoint LOD scores for extended pedigrees rapidly becomes infeasible as the number of markers and untyped individuals increase. When markers are exc...
Cornelis A. Albers, Martijn A. R. Leisink, Hilbert...
BMCBI
2006
135views more  BMCBI 2006»
13 years 9 months ago
Correcting ligands, metabolites, and pathways
Background: A wide range of research areas in bioinformatics, molecular biology and medicinal chemistry require precise chemical structure information about molecules and reaction...
Martin A. Ott, Gert Vriend
BMCBI
2006
131views more  BMCBI 2006»
13 years 9 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller
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