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BMCBI
2004
150views more  BMCBI 2004»
13 years 9 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty
BMCBI
2004
114views more  BMCBI 2004»
13 years 9 months ago
Extending the mutual information measure to rank inferred literature relationships
Background: Within the peer-reviewed literature, associations between two things are not always recognized until commonalities between them become apparent. These commonalities ca...
Jonathan D. Wren
BMCBI
2004
132views more  BMCBI 2004»
13 years 9 months ago
Two-stage normalization using background intensities in cDNA microarray data
Background: In the microarray experiment, many undesirable systematic variations are commonly observed. Normalization is the process of removing such variation that affects the me...
Dankyu Yoon, Sung-Gon Yi, Ju-Han Kim, Taesung Park
BMCBI
2004
142views more  BMCBI 2004»
13 years 9 months ago
GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies
Background: Microarray and other high-throughput technologies are producing large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed...
Bing Zhang, Denise Schmoyer, Stefan Kirov, Jay Sno...
BMCBI
2004
112views more  BMCBI 2004»
13 years 9 months ago
A double classification tree search algorithm for index SNP selection
Background: In population-based studies, it is generally recognized that single nucleotide polymorphism (SNP) markers are not independent. Rather, they are carried by haplotypes, ...
Peisen Zhang, Huitao Sheng, Ryuhei Uehara
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