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BMCBI
2006
13 years 9 months ago
2006
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
BMCBI
2006
13 years 9 months ago
2006
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
BMCBI
2006
13 years 9 months ago
2006
Background: Cross-validation (CV) is an effective method for estimating the prediction error of a classifier. Some recent articles have proposed methods for optimizing classifiers...
BMCBI
2006
13 years 9 months ago
2006
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
BMCBI
2006
13 years 9 months ago
2006
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...