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BMCBI
2005
131views more  BMCBI 2005»
15 years 4 months ago
Functional annotation by identification of local surface similarities: a novel tool for structural genomics
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
Fabrizio Ferrè, Gabriele Ausiello, Andreas ...
BMCBI
2005
115views more  BMCBI 2005»
15 years 4 months ago
SUPERFICIAL - Surface mapping of proteins via structure-based peptide library design
Background: The determination of protein surfaces and the detection of binding sites are essential to our understanding of protein-protein interactions. Such binding sites can be ...
Andrean Goede, Ines S. Jaeger, Robert Preissner
BMCBI
2005
112views more  BMCBI 2005»
15 years 4 months ago
Visualization methods for statistical analysis of microarray clusters
Background: The most common method of identifying groups of functionally related genes in microarray data is to apply a clustering algorithm. However, it is impossible to determin...
Matthew A. Hibbs, Nathaniel C. Dirksen, Kai Li, Ol...
BMCBI
2005
163views more  BMCBI 2005»
15 years 4 months ago
Rank-invariant resampling based estimation of false discovery rate for analysis of small sample microarray data
Background: The evaluation of statistical significance has become a critical process in identifying differentially expressed genes in microarray studies. Classical p-value adjustm...
Nitin Jain, HyungJun Cho, Michael O'Connell, Jae K...
JAR
2007
104views more  JAR 2007»
15 years 4 months ago
Student Proof Exercises Using MathsTiles and Isabelle/HOL in an Intelligent Book
The Intelligent Book project aims to improve online education by designing materials that can model the subject matter they teach, in the manner of a Reactive Learning Environment...
William Billingsley, Peter Robinson