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RECOMB
2002
Springer
14 years 11 months ago
An Overview of Combinatorial Methods for Haplotype Inference
A current high-priority phase of human genomics involves the development of a full Haplotype Map of the human genome [23]. It will be used in large-scale screens of populations to...
Dan Gusfield
RECOMB
2002
Springer
14 years 11 months ago
Significance Of inter-species matches when evolutionary rate varies
We develop techniques to estimate the statistical significance of gap-free alignments between two genomic DNA sequences, using human-mouse alignments as an example. The sequences ...
Jia Li, Webb Miller
RECOMB
2002
Springer
14 years 11 months ago
Combining pairwise sequence similarity and support vector machines for remote protein homology detection
One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of i...
Li Liao, William Stafford Noble
RECOMB
2002
Springer
14 years 11 months ago
Provably sensitive Indexing strategies for biosequence similarity search
The field of algorithms for pairwisc biosequence similarity search is dominated by heuristic methods of high efficiency but uncertain sensitivity. One reason that more formal stri...
Jeremy Buhler
RECOMB
2002
Springer
14 years 11 months ago
Deconvolving sequence variation in mixed DNA populations
We present an original approach to identifying sequence variants in a mixed DNA population from sequence trace data. The heart of the method is based on parsimony: given a wildtyp...
Andy Wildenberg, Steven Skiena, Pavel Sumazin