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RECOMB
2003
Springer
14 years 10 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
RECOMB
2003
Springer
14 years 10 months ago
Accurate detection of very sparse sequence motifs
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
Andreas Heger, Michael Lappe, Liisa Holm
RECOMB
2003
Springer
14 years 10 months ago
Whole-genome comparative annotation and regulatory motif discovery in multiple yeast species
In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae. Genome-wide comp...
Manolis Kamvysselis, Nick Patterson, Bruce Birren,...
RECOMB
2003
Springer
14 years 10 months ago
Large scale reconstruction of haplotypes from genotype data
Critical to the understanding of the genetic basis for complex diseases is the modeling of human variation. Most of this variation can be characterized by single nucleotide polymo...
Eleazar Eskin, Eran Halperin, Richard M. Karp
RECOMB
2003
Springer
14 years 10 months ago
Joint classifier and feature optimization for cancer diagnosis using gene expression data
Recent research has demonstrated quite convincingly that accurate cancer diagnosis can be achieved by constructing classifiers that are designed to compare the gene expression pro...
Balaji Krishnapuram, Lawrence Carin, Alexander J. ...