In the past years, many combinatorial arguments have been made to support the theory that mammalian genome rearrangement scenarios rely heavily on breakpoint reuse. Different model...
Abstract. Contemporary inferences about evolution occasionally involve analyzing infinitely large feature spaces, requiring specific algorithmic techniques. We consider parsimony a...
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Following various genetic mapping techniques conducted on different segregating populations, one or more genetic maps are obtained for a given species. However, recombination analy...
Abstract. The recent availability of large scale data sets profiling single nucleotide polymorphisms (SNPs) and gene expression across different human populations, has directed muc...
Oliver Stegle, Anitha Kannan, Richard Durbin, John...