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BMCBI
2010
87views more  BMCBI 2010»
13 years 10 months ago
poolMC: Smart pooling of mRNA samples in microarray experiments
Background: Typically, pooling of mRNA samples in microarray experiments implies mixing mRNA from several biological-replicate samples before hybridization onto a microarray chip....
Raghunandan M. Kainkaryam, Angela Bruex, Anna C. G...
BMCBI
2010
104views more  BMCBI 2010»
13 years 10 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
BMCBI
2010
155views more  BMCBI 2010»
13 years 10 months ago
FunctSNP: an R package to link SNPs to functional knowledge and dbAutoMaker: a suite of Perl scripts to build SNP databases
Background: Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a ...
Stephen J. Goodswen, Cedric Gondro, Nathan S. Wats...
BMCBI
2010
175views more  BMCBI 2010»
13 years 10 months ago
Calibur: a tool for clustering large numbers of protein decoys
Background: Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of...
Shuai Cheng Li, Yen Kaow Ng
BMCBI
2010
133views more  BMCBI 2010»
13 years 10 months ago
Consolidating metabolite identifiers to enable contextual and multi-platform metabolomics data analysis
Background: Analysis of data from high-throughput experiments depends on the availability of well-structured data that describe the assayed biomolecules. Procedures for obtaining ...
Henning Redestig, Miyako Kusano, Atsushi Fukushima...