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BMCBI
2010
13 years 10 months ago
2010
Background: Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software. This f...
BMCBI
2010
13 years 10 months ago
2010
Background: A simple classification rule with few genes and parameters is desirable when applying a classification rule to new data. One popular simple classification rule, diagon...
BMCBI
2010
13 years 10 months ago
2010
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
BMCBI
2010
2010
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
13 years 10 months ago
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
BMCBI
2010
13 years 10 months ago
2010
Background: Functional genomic studies involving high-throughput sequencing and tiling array applications, such as ChIP-seq and ChIP-chip, generate large numbers of experimentally...