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TCBB
2011
13 years 5 months ago
Visual Exploration across Biomedical Databases
Abstract—Though biomedical research often draws on knowledge from a wide variety of fields, few visualization methods for biomedical data incorporate meaningful cross-database e...
Michael D. Lieberman, Sima Taheri, Huimin Guo, Fat...
TCBB
2011
13 years 5 months ago
Learning Genetic Regulatory Network Connectivity from Time Series Data
Recent experimental advances facilitate the collection of time series data that indicate which genes in a cell are expressed. This paper proposes an efficient method to generate th...
Nathan A. Barker, Chris J. Myers, Hiroyuki Kuwahar...
TCBB
2011
13 years 5 months ago
Information-Theoretic Model of Evolution over Protein Communication Channel
—In this paper, we propose a communication model of evolution and investigate its information-theoretic bounds. The process of evolution is modeled as the retransmission of infor...
Liuling Gong, Nidhal Bouaynaya, Dan Schonfeld
TCBB
2011
13 years 5 months ago
Accurate Construction of Consensus Genetic Maps via Integer Linear Programming
—We study the problem of merging genetic maps, when the individual genetic maps are given as directed acyclic graphs. The computational problem is to build a consensus map, which...
Yonghui Wu, Timothy J. Close, Stefano Lonardi
TCBB
2011
13 years 5 months ago
Ensemble Learning with Active Example Selection for Imbalanced Biomedical Data Classification
—In biomedical data, the imbalanced data problem occurs frequently and causes poor prediction performance for minority classes. It is because the trained classifiers are mostly d...
Sangyoon Oh, Min Su Lee, Byoung-Tak Zhang