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BMCBI
2006
126views more  BMCBI 2006»
13 years 10 months ago
Genomes as geography: using GIS technology to build interactive genome feature maps
Background: Many commonly used genome browsers display sequence annotations and related attributes as horizontal data tracks that can be toggled on and off according to user prefe...
Mary E. Dolan, Constance C. Holden, M. Kate Beard,...
BMCBI
2006
130views more  BMCBI 2006»
13 years 10 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
BMCBI
2006
100views more  BMCBI 2006»
13 years 10 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
BMCBI
2006
153views more  BMCBI 2006»
13 years 10 months ago
Automatic document classification of biological literature
Background: Document classification is a wide-spread problem with many applications, from organizing search engine snippets to spam filtering. We previously described Textpresso, ...
David Chen, Hans-Michael Müller, Paul W. Ster...
BMCBI
2006
133views more  BMCBI 2006»
13 years 10 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
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