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BMCBI
2010
13 years 11 months ago
2010
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
BMCBI
2010
13 years 11 months ago
2010
Background: Scoring functions, such as molecular mechanic forcefields and statistical potentials are fundamentally important tools in protein structure modeling and quality assess...
BMCBI
2010
13 years 11 months ago
2010
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
BMCBI
2010
13 years 11 months ago
2010
Background: Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software. This f...
BMCBI
2010
13 years 11 months ago
2010
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...