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BMCBI
2010
116views more  BMCBI 2010»
13 years 7 months ago
SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments
Background: High throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these ...
David B. Burdick, Christopher C. Cavnor, Jeremy Ha...
BMCBI
2010
96views more  BMCBI 2010»
13 years 7 months ago
OpenChrom: a cross-platform open source software for the mass spectrometric analysis of chromatographic data
Background: Today, data evaluation has become a bottleneck in chromatographic science. Analytical instruments equipped with automated samplers yield large amounts of measurement d...
Philip Wenig, Juergen Odermatt
BMCBI
2010
151views more  BMCBI 2010»
13 years 7 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...
BMCBI
2010
161views more  BMCBI 2010»
13 years 7 months ago
BPDA - A Bayesian peptide detection algorithm for mass spectrometry
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
Youting Sun, Jianqiu Zhang, Ulisses Braga-Neto, Ed...
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani