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BMCBI
2011
14 years 7 months ago
A Novel And Well-Defined Benchmarking Method For Second Generation Read Mapping
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
BMCBI
2011
14 years 7 months ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...
PLDI
2011
ACM
14 years 6 months ago
Finding and understanding bugs in C compilers
Compilers should be correct. To improve the quality of C compilers, we created Csmith, a randomized test-case generation tool, and spent three years using it to find compiler bug...
Xuejun Yang, Yang Chen, Eric Eide, John Regehr
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BMCBI
2011
14 years 7 months ago
SeqGene: a comprehensive software solution for mining exome- and transcriptome- sequencing data
Background: The popularity of massively parallel exome and transcriptome sequencing projects demands new data mining tools with a comprehensive set of features to support a wide r...
Xutao Deng
CCS
2011
ACM
14 years 3 months ago
Fear the EAR: discovering and mitigating execution after redirect vulnerabilities
The complexity of modern web applications makes it difficult for developers to fully understand the security implications of their code. Attackers exploit the resulting security v...
Adam Doupé, Bryce Boe, Christopher Kruegel,...