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BIOINFORMATICS
2006
15 years 4 months ago
2006
Motivation: Intervention in a gene regulatory network is used to avoid undesirable states, such as those associated with a disease. Several types of intervention have been studied...
157
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BMCBI
2006
15 years 4 months ago
2006
Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
129
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BMCBI
2006
15 years 4 months ago
2006
Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique to examine post-translational modifications of complexly modulated proteins. Currently, spot detectio...
102
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BMCBI
2006
15 years 4 months ago
2006
Background: T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a...
120
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BMCBI
2006
15 years 4 months ago
2006
Background: Gene expression microarray data is notoriously subject to high signal variability. Moreover, unavoidable variation in the concentration of transcripts applied to micro...